Search results for "gene evolution"

showing 5 items of 5 documents

GENE STRUCTURE, DIFFERENTIAL EXPRESSION AND PHYLOGENETIC ANALYSIS OF THE METALLOTHIONEIN GENE FAMILY OF THE SEA URCHIN PARACENTROTUS LIVIDUS

2017

Metallothioneins (MT) are small and cysteine-rich proteins that bind metal ions such as zinc, copper, cadmium, and nickel1. Several functions were proposed for these peptides, ranging from toxic metal protection to physiological metal homeostasis, free radical scavenging, oxidative stress protection, antiapoptotic defense, control of the redox status of the cell and also roles during development. Previously, we reported the identification of five different MT homologues (PlMT4-8) from the Mediterranean sea urchin species P. lividus2. In order to shed some light on MT gene structure and evolution, we cloned seven P. lividus MT genes, comparing them to Echinodermata and Chordata genes3. Moreo…

Metallothioneins embryo development metals stress gene evolution gene expression.Settore BIO/11 - Biologia Molecolare
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Transcriptomic data from panarthropods shed new light on the evolution of insulator binding proteins in insects : Insect insulator proteins.

2016

Background Body plan development in multi-cellular organisms is largely determined by homeotic genes. Expression of homeotic genes, in turn, is partially regulated by insulator binding proteins (IBPs). While only a few enhancer blocking IBPs have been identified in vertebrates, the common fruit fly Drosophila melanogaster harbors at least twelve different enhancer blocking IBPs. We screened recently compiled insect transcriptomes from the 1KITE project and genomic and transcriptomic data from public databases, aiming to trace the origin of IBPs in insects and other arthropods. Results Our study shows that the last common ancestor of insects (Hexapoda) already possessed a substantial number …

0301 basic medicineMost recent common ancestormedia_common.quotation_subjectInsectDipluraGene evolutionEvolution Molecular03 medical and health sciencesArthropod evolutionGeneticsAnimalsEnhancerArthropodsPhylogenymedia_commonGeneticsbiologyGene Expression ProfilingfungiComparative transcriptomic analysesbiology.organism_classificationInsulator binding proteinsNeopteraDNA-Binding Proteins030104 developmental biologyBody planDrosophila melanogasterEnhancer Elements GeneticInsulator ElementsDrosophila melanogasterHomeotic geneTranscriptomeBiotechnologyResearch ArticleBMC genomics
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Distinct bhaplotype structure at the innate immune receptor Toll-like receptor 2 across bank vole populations and lineages in Europe

2015

Abstract: Parasite-mediated selection may contribute to the maintenance of genetic variation at host immune genes over long time scales. To date, the best evidence for the long-term maintenance of immunogenetic variation in natural populations comes from studies on the major histocompatibility complex (MHC) genes, whereas evidence for such processes from other immune genes remains scarce. In the present study, we show that, despite pronounced population differentiation and the occurrence of numerous private alleles within populations, the innate immune gene Toll-like receptor 2 (TLR2) displays a distinct haplotype structure in 21 bank vole (Myodes glareolus) populations across Europe. Haplo…

balancing selectionPopulationphylogeographyBalancing selectionMajor histocompatibility complexToxicologydiversitypolymorphismsmall mammalspositive darwinian selectionMyodes glareolusGenetic variationmaintenance of genetic variationTLR2mhceducationclethrionomys-glareolusBiologyEcology Evolution Behavior and SystematicsToxicologieVLAGGeneticseducation.field_of_studyToll-like receptorInnate immune systembiologyHaplotypebiology.organism_classificationmajor histocompatibility complexparasite resistanceimmunogeneticsBank voleEvolutionary biologynorthern spaingene evolutionbiology.proteinta1181genetic-variationroderentscontrasting patterns
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Transcriptomic data from panarthropods shed new light on the evolution of insulator binding proteins in insects

2016

BACKGROUND: Body plan development in multi-cellular organisms is largely determined by homeotic genes. Expression of homeotic genes, in turn, is partially regulated by insulator binding proteins (IBPs). While only a few enhancer blocking IBPs have been identified in vertebrates, the common fruit fly Drosophila melanogaster harbors at least twelve different enhancer blocking IBPs. We screened recently compiled insect transcriptomes from the 1KITE project and genomic and transcriptomic data from public databases, aiming to trace the origin of IBPs in insects and other arthropods. RESULTS: Our study shows that the last common ancestor of insects (Hexapoda) already possessed a substantial numbe…

Arthropod evolutionGene evolution ; Insulator binding proteins ; Comparative transcriptomic analyses ; Arthropod evolutionfungiGeneticsComparative transcriptomic analysesInsulator binding proteinsGene evolutionBiotechnologyBMC Genomics
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Data from: Transcriptomic data from panarthropods shed new light on the evolution of insulator binding proteins in insects

2017

Background Body plan development in multi-cellular organisms is largely determined by homeotic genes. Expression of homeotic genes, in turn, is partially regulated by insulator binding proteins (IBPs). While only a few enhancer blocking IBPs have been identified in vertebrates, the common fruit fly Drosophila melanogaster harbors at least twelve different enhancer blocking IBPs. We screened recently compiled insect transcriptomes from the 1KITE project and genomic and transcriptomic data from public databases, aiming to trace the origin of IBPs in insects and other arthropods. Results Our study shows that the last common ancestor of insects (Hexapoda) already possessed a substantial number …

medicine and health careArthropod evolutionfungiMedicineComparative transcriptomic analysesInsulator binding proteinsLife sciencesGene evolution
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